@inbook {1354, title = {Studierende als Forschungssubjekte in Hochschullernwerkst{\"a}tten. {\quotesinglbase}Was willst DU lernen?!{\textquoteleft} {\textendash} Teil IV}, booktitle = {Demokratie und Partizipation in Hochschullernwerkst{\"a}tten}, volume = {12, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2024}, pages = {248-260}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kelkel, Mareike and Kihm, Pascal and Peschel, Markus}, editor = {Franz, Viktoria Sophie and Langhof, Julia Kristin and Simon, Jana and Franz, Eva-Kristina} } @inbook {1320, title = {Einleitung {\textendash} Einsichten zu Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten}, booktitle = {Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten. Theorien, Praktiken, Utopien}, volume = {11, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2023}, pages = {11-21}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kihm, Pascal and Peschel, Markus and Kelkel, Mareike}, editor = {Kihm, Pascal and Kelkel, Mareike and Peschel, Markus} } @booklet {1325, title = {Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten. Theorien, Praktiken, Utopien}, volume = {11, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2023}, publisher = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, isbn = {978-3-7815-6009-3}, doi = {doi.org/10.35468/6009}, author = {Kihm, Pascal and Kelkel, Mareike and Peschel, Markus} } @inbook {1322, title = {Nonvokalit{\"a}ten und Lehr-Lern-Prozesse {\textendash} Eine (Sekund{\"a}r-)Analyse von Unterrichtsvideos zu Kommunikationseinfl{\"u}ssen beim Experimentieren in Lernwerkst{\"a}tten, Sch{\"u}lerlaboren und im Schulunterricht}, booktitle = {Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten. Theorien, Praktiken, Utopien}, volume = {11, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2023}, pages = {71-88}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kihm, Pascal and Peifer, Patrick and Peschel, Markus}, editor = {Kihm, Pascal and Kelkel, Mareike and Peschel, Markus} } @inbook {1321, title = {Ph{\"a}nomenbasiertes Experimentieren in (Hochschul-)Lernwerkst{\"a}tten}, booktitle = {Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten. Theorien, Praktiken, Utopien}, volume = {11, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2023}, pages = {102-119}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Fischer, Marie and Peschel, Markus}, editor = {Kihm, Pascal and Kelkel, Mareike and Peschel, Markus} } @inbook {1323, title = {Tiefenstrukturen von Interaktions- und Kommunikationsprozessen in Hochschullernwerkst{\"a}tten}, booktitle = {Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten. Theorien, Praktiken, Utopien}, volume = {11, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2023}, pages = {25-45}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kihm, Pascal}, editor = {Kihm, Pascal and Kelkel, Mareike and Peschel, Markus} } @inbook {1324, title = {{\quotesinglbase}Was willst du lernen?{\textquoteleft} {\textendash} Teil II. Irritationen {\"a}ndern Beliefs in Hochschullernwerkstattseminaren}, booktitle = {Interaktionen und Kommunikationen in Hochschullernwerkst{\"a}tten. Theorien, Praktiken, Utopien}, volume = {11, Lernen und Studieren in Lernwerkst{\"a}tten. Impulse f{\"u}r Theorie und Praxis}, year = {2023}, pages = {287-302}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kelkel, Mareike and Peschel, Markus}, editor = {Kihm, Pascal and Kelkel, Mareike and Peschel, Markus} } @inbook {1247, title = {Offline- vs. Online-Formate {\textendash} Eine Gegen{\"u}berstellung verschiedener Formate GOFEX-Pr{\"a}sentationen}, booktitle = {GDSU-Journal, M{\"a}rz 2022}, volume = {13}, year = {2022}, pages = {102-104}, publisher = {GDSU e. V.}, organization = {GDSU e. V.}, address = {Berlin}, author = {Kelkel, Mareike and Peschel, Markus}, editor = {Diederich, Julia and Schr{\"o}er, Franz and Goll, Thomas} } @inbook {1177, title = {Das Projekt SCIENCE without FICTION innerhalb des Reality-Virtuality-Continuum}, booktitle = {Naturwissenschaftlicher Unterricht und Lehrerbildung im Umbruch? Gesellschaft f{\"u}r Didaktik der Chemie und Physik. Jahrestagung in Aachen 2020}, volume = {41, Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, year = {2021}, pages = {374-377}, publisher = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, organization = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, address = {Regensburg}, url = {https://www.gdcp-ev.de/wp-content/tb2021/TB2021_374_Lang.pdf}, author = {Lang, Vanessa and Seibert, Johann and Eichinger, Annika and Bach, Sarah and Kelkel, Mareike and Peschel, Markus and Perels, Franziska and Kay, Christopher W.}, editor = {Habig, Sebastian} } @inbook {1193, title = {Hochschullernwerkst{\"a}tten und Lernwerkst{\"a}tten {\textendash} Verortung in didaktischen Diskursen}, booktitle = {lern.medien.werk.statt. Hochschullernwerkst{\"a}tten in der Digitalit{\"a}t}, volume = {9, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2021}, pages = {40-53}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, url = {https://klinkhardt.de/verlagsprogramm/2468.html}, author = {Peschel, Markus and Wedekind, Hartmut and Kihm, Pascal and Kelkel, Mareike}, editor = {Holub, Barbara and Himpsl-Gutermann, Klaus and Mittlb{\"o}ck, Katharina and Musilek-Hofer, Monika and Varelija-Gerber, Andrea and Gr{\"u}nberger, Nina} } @inbook {1176, title = {Kompetenzentwicklung durch didaktisch eingebettete Augmented Reality}, booktitle = {Naturwissenschaftlicher Unterricht und Lehrerbildung im Umbruch? Gesellschaft f{\"u}r Didaktik der Chemie und Physik. Jahrestagung in Aachen 2020}, volume = {41, Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, year = {2021}, pages = {370-373}, publisher = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, organization = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, address = {Regensburg}, url = {https://www.gdcp-ev.de/wp-content/tb2021/TB2021_370_Kay.pdf}, author = {Kay, Christopher W. and Peschel, Markus and Perels, Franziska and Lauer, Luisa and Seibert, Johann and Lang, Vanessa and Eichinger, Annika and Bach, Sarah and Kelkel, Mareike}, editor = {Habig, Sebastian} } @inbook {1175, title = {Kompetenzentwicklung f{\"u}r die Naturwissenschaften durch Augmented Reality}, booktitle = {Naturwissenschaftlicher Unterricht und Lehrerbildung im Umbruch? Gesellschaft f{\"u}r Didaktik der Chemie und Physik. Jahrestagung in Aachen 2020}, volume = {41, Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, year = {2021}, pages = {362-365}, publisher = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, organization = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, address = {Regensburg}, url = {https://www.gdcp-ev.de/wp-content/tb2021/TB2021_362_Kay.pdf}, author = {Kay, Christopher W. and Peschel, Markus and Perels, Franziska and Bach, Sarah and Kelkel, Mareike and Lauer, Luisa and Seibert, Johann and Lang, Vanessa and Eichinger, Annika}, editor = {Habig, Sebastian} } @inbook {1192, title = {Potenziale der p{\"a}dagogisch-didaktischen {\"O}ffnung in Hochschullernwerkst{\"a}tten}, booktitle = {lern.medien.werk.statt. Hochschullernwerkst{\"a}tten in der Digitalit{\"a}t}, volume = {9, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2021}, pages = {321-334}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, url = {https://klinkhardt.de/verlagsprogramm/2468.html}, author = {Kelkel, Mareike and Peschel, Markus and Kihm, Pascal}, editor = {Holub, Barbara and Himpsl-Gutermann, Klaus and Mittlb{\"o}ck, Katharina and Musilek-Hofer, Monika and Varelija-Gerber, Andrea and Gr{\"u}nberger, Nina} } @inbook {1174, title = {QUANTAG: Augmented-Reality-Campus-Rallye als Einstieg in die Quantentechnologie}, booktitle = {Naturwissenschaftlicher Unterricht und Lehrerbildung im Umbruch? Gesellschaft f{\"u}r Didaktik der Chemie und Physik. Jahrestagung in Aachen 2020}, volume = {41, Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, year = {2021}, pages = {366-369}, publisher = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, organization = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, address = {Regensburg}, url = {https://www.gdcp-ev.de/wp-content/tb2021/TB2021_366_Eichinger.pdf}, author = {Eichinger, Annika and Schmoll, Isabel and Kelkel, Mareike and Seibert, Johann and Lauer, Luisa and Lang, Vanessa and Bach, Sarah and Perels, Franziska and Kay, Christopher W. and Peschel, Markus}, editor = {Habig, Sebastian} } @inbook {1164, title = {Untersuchung der Wirkungen von AR-Visualisierungstechniken in der Primarstufe}, booktitle = {Naturwissenschaftlicher Unterricht und Lehrerbildung im Umbruch? Gesellschaft f{\"u}r Didaktik der Chemie und Physik. Jahrestagung in Aachen 2020}, volume = {41, Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, year = {2021}, pages = {378-381}, publisher = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, organization = {Gesellschaft f{\"u}r Didaktik der Chemie und Physik (GDCP)}, address = {Regensburg}, url = {https://www.gdcp-ev.de/wp-content/tb2021/TB2021_378_Lauer.pdf}, author = {Lauer, Luisa and Peschel, Markus and Seibert, Johann and Vanessa Lang and Eichinger, Annika and Kristin Altmeyer and Sarah Malone and Kelkel, Mareike and Bach, Sarah and Perels, Franziska and Kay, Christopher W.}, editor = {Habig, Sebastian} } @inbook {1077, title = {Professionalisierung von Lehramtsstudierenden im GOFEX_Projektpraktikum durch Studierenden-Co-Reflexion}, booktitle = {Spielen, Lernen, Arbeiten in Lernwerkst{\"a}tten. Facetten der Kooperation und Kollaboration.}, volume = {7, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2020}, pages = {64-77}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kelkel, Mareike and Peschel, Markus}, editor = {Stadler-Altmann, Ulrike and Schumacher, Susanne and Emili, Enrico Angelo and Dalla Torre, Elisabeth} } @inbook {1076, title = {F{\"o}rderung der beruflichen Handlungsf{\"a}higkeit von Studierenden im Sachunterricht durch das GOFEX_Projektpraktikum}, booktitle = {Perspektiven auf Hochschullernwerkst{\"a}tten. Wechselspiele zwischen Individuum, Gemeinschaft, Ding und Raum}, volume = {6, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2019}, pages = {157-167}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kelkel, Mareike and Peschel, Markus}, editor = {T{\"a}nzer, Sandra and Godau, Marc and Berger, Markus and Mannhaupt, G.} } @inbook {1039, title = {Lernwerkst{\"a}tten und Sch{\"u}lerlabore {\textendash} Unterschiedliche Konzepte, ein Verbund. Kooperation zwischen GOFEX und NanoBioLab im Rahmen des GOFEX-Projektpraktikums als Beispiel f{\"u}r kooperatives Lernen}, booktitle = {Struktur und Handlung in Lernwerkst{\"a}tten. Hochschuldidaktische R{\"a}ume zwischen Einschr{\"a}nkung und Erm{\"o}glichung}, volume = {5, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2019}, pages = {185-189}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kelkel, Mareike and Peschel, Markus}, editor = {Baar, Robert and Feindt, Andreas and Trostmann, Sven} } @inbook {942, title = {Fachlichkeit in Lernwerkst{\"a}tten}, booktitle = {Fachlichkeit in Lernwerkst{\"a}tten {\textendash} Kind und Sache in Lernwerkst{\"a}tten}, volume = {4, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2018}, pages = {15-34}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kelkel, Mareike and Peschel, Markus}, editor = {Peschel, Markus and Kelkel, Mareike} } @booklet {809, title = {Fachlichkeit in Lernwerkst{\"a}tten. Kind und Sache in Lernwerkst{\"a}tten}, volume = {4, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2018}, publisher = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, isbn = {978-3-7815-2244-2}, doi = {doi.org/10.35468/5652}, url = {https://klinkhardt.de/verlagsprogramm/2244.html}, author = {Peschel, Markus and Kelkel, Mareike} } @inbook {936, title = {Kinder forschen {\textendash} Wege zur (gemeinsamen) Erkenntnis}, booktitle = {Fachlichkeit in Lernwerkst{\"a}tten. Kind und Sache in Lernwerkst{\"a}tten.}, volume = {4, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2018}, pages = {66-84}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Kihm, Pascal and Diener, Jenny and Peschel, Markus}, editor = {Peschel, Markus and Kelkel, Mareike} } @inbook {943, title = {Potenziale von Lernwerkst{\"a}tten zur Vermittlung von Handlungskompetenzen angehender Lehrkr{\"a}fte. Chancen von Verb{\"u}nden im Rahmen der Qualit{\"a}tsoffensive Lehrerbildung}, booktitle = {GDSU-Journal, Juni 2018}, volume = {8}, year = {2018}, pages = {31-46}, publisher = {GDSU e. V.}, organization = {GDSU e. V.}, address = {Berlin}, author = {Peschel, M. and Kelkel, Mareike}, editor = {Giest, Hartmut and Hartinger, Andreas and Franz, Ute} } @inbook {941, title = {Zur Sache!}, booktitle = {Fachlichkeit in Lernwerkst{\"a}tten {\textendash} Kind und Sache in Lernwerkst{\"a}tten}, volume = {4, Lernen und Studieren in Lernwerkst{\"a}tten}, year = {2018}, pages = {9-14}, publisher = {Verlag Julius Klinkhardt}, organization = {Verlag Julius Klinkhardt}, address = {Bad Heilbrunn}, author = {Peschel, M. and Kelkel, Mareike}, editor = {Peschel, M. and Kelkel, Mareike} } @inbook {979, title = {Einstellungen zum Experimentieren im Lehramt Primarstufe}, booktitle = {LeLa Magazin}, volume = {M{\"a}rz 2017}, year = {2017}, pages = {12-13}, edition = {17}, author = {Peschel, Markus and Kihm, Pascal and Scherer, Nele and Kelkel, Mareike} } @article {787, title = {GOFEX_EE {\textendash} Erneuerbare Energien im praktischen Test}, journal = {LeLa BNE Brosch{\"u}re "Bildung f{\"u}r nachhaltige Entwicklung in Sch{\"u}lerlaboren"}, year = {2016}, pages = {62-65}, author = {Kelkel, Mareike and Peschel, Markus and Urig, Nele} } @inbook {980, title = {Towards pharmaceutically useful, redox-modulating polysulfanes based on naturally occurring garlic compounds}, booktitle = {Food and Chemical Toxicology}, volume = {64}, year = {2014}, pages = {249-257}, author = {Czepukojc, Brigitte and Baltes, Anne-Kathrin and Kelkel, Mareike and Cerella, Claudia and Maheswari Viswanathan, Uma and Salm, Franz and Burkholz, Thorsten and Schneider, Carolin C. and Montenarh, Mathias and Diederich, Marc F. and Jacob, Claus} } @inbook {694, title = {Wer macht die Nacht? {\textendash} Das Ph{\"a}nomen Nacht naturwissenschaftlich erkunden}, booktitle = {kindergarten heute}, volume = {06/2014}, year = {2014}, pages = {32-34}, publisher = {Verlag Herder}, organization = {Verlag Herder}, address = {Freiburg i. Br.}, author = {Kelkel, Mareike and Peschel, Markus} } @inbook {1026, title = {Synthetic polysulfane derivatives induce cell cycle arrest and apoptotic cell death in human hematopoietic cancer cells}, booktitle = {Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association 64}, year = {2013}, author = {Czepukojc, Brigitte and Baltes, Anne-Kathrin and Cerella, Claudia and Kelkel, Mareike and Maheswari Viswanathan, Uma and Salm, Franz and Burkholz, Thorsten and Schneider, Carolin C. and Dicato, Mario and Montenarh, Mathias and Jacob, Claus and Diederich, Marc F.} } @inbook {981, title = {ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis}, booktitle = {Carcinogenesis}, volume = {33}, year = {2012}, pages = {2162-2171}, edition = {11}, author = {Kelkel, Mareike and Cerella, Claudia and Mack, F. and Schneider, T. and Jacob, Claus and Schumacher, Marc and Dicato, Mario and Diederich, Marc F.} } @inbook {982, title = {Antioxidant and anti-proliferative properties of lycopene}, booktitle = {Free Radical Research}, volume = {45}, year = {2011}, pages = {925-940}, edition = {8}, doi = { 10.3109/10715762.2011.564168}, author = {Kelkel, Mareike and Schumacher, Marc and Dicato, Mario and Diederich, Marc F.} } @inbook {986, title = {Gold from the sea: Marine compounds as inhibitors of the hallmarks of cancer}, booktitle = {Biotechnology Advances}, volume = {29}, year = {2011}, pages = {531-547}, edition = {5}, abstract = {

Cancer is one of the most deadly diseases in the world. Although advances in the field of chemo-preventive and therapeutic medicine have been made regularly over the last ten years, the search for novel anticancer treatments continues. In this field, the marine environment, with its rich variety of organisms, is a largely untapped source of novel compounds with potent antitumor activity. Although many reviews of marine anticancer compounds have been published, we focus here on selected marine compounds that act on the six hallmarks of cancer presented namely self-sufficiency in growth signals, insensitivity to anti-growth signals, evasion of apoptosis, limitless replication, sustained angiogenesis and tissue invasion and metastasis.

}, author = {Schumacher, Marc and Kelkel, Mareike and Dicato, Mario and Diederich, Marc F.} } @inbook {988, title = {Naturally Occurring Organic Sulfur Compounds: An Example of a Multitasking Class of Phytochemicals in Anti-Cancer Research}, booktitle = {Phytochemcials}, year = {2011}, author = {Cerella, Claudia and Kelkel, Mareike and Viry, Elodie and Dicato, Mario and Jacob, Claus and Diederich, Marc F.} } @inbook {983, title = {Selective Antimicrobial Activity Associated with Sulfur Nanoparticles}, booktitle = {Journal of Biomedical Nanotechnology}, volume = {7}, year = {2011}, pages = {395405}, edition = {3}, doi = {10.1166/jbn.2011.1293}, author = {Schneider, T. and Baldauf, A. and Schneider, M. and Burkholz, T. and Kelkel, Mareike and Jacob, Claus} } @inbook {987, title = {A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2010}, booktitle = {molecules}, volume = {16}, year = {2011}, pages = {5629-5646}, abstract = {

Although considerable progress in oncology therapeutics has been achieved in the last century, cancer remains one of major death causes in the World and for this reason, the development of novel cancer drugs remains a pressing need. Natural marine compounds represent an interesting source of novel leads with potent chemotherapeutic or chemo-preventive activities. In the last decades, structure-activity-relationship studies have led to the development of naturally-derived or semi-synthetic analogues with improved bioactivity, a simplified synthetic target or less toxicity. We aim here to review a selection of natural compounds with reported anticancer activity isolated of marine sources and their associated analogues published in 2010.

}, doi = {10.3390/molecules16075629}, author = {Schumacher, Marc and Kelkel, Mareike and Dicato, Mario and Diederich, Marc F.} } @inbook {1025, title = {Decrypting the labyrinth of inflammatory cell signaling pathways: Editorial to the meeting "Inflammation 2010"}, booktitle = {Journal of Cell Communication and Signaling 4(4)}, year = {2010}, pages = {159-60}, author = {Kelkel, Mareike and Boyer-Orlikova, Barbora and Diederich, Marc F.} } @inbook {989, title = {Potential of the Dietary Antioxidants Resveratrol and Curcumin in Prevention and Treatment of Hematologic Malignancie}, booktitle = {Molecules}, volume = {15}, year = {2010}, pages = {7035-7074}, edition = {10}, abstract = {

Despite considerable improvements in the tolerance and efficacy of novel chemotherapeutic agents, the mortality of hematological malignancies is still high due to therapy relapse, which is associated with bad prognosis. Dietary polyphenolic compounds are of growing interest as an alternative approach, especially in cancer treatment, as they have been proven to be safe and display strong antioxidant properties. Here, we provide evidence that both resveratrol and curcumin possess huge potential for application as both chemopreventive agents and anticancer drugs and might represent promising candidates for future treatment of leukemia. Both polyphenols are currently being tested in clinical trials. We describe the underlying mechanisms, but also focus on possible limitations and how they might be overcome in future clinical use--either by chemically synthesized derivatives or special formulations that improve bioavailability and pharmacokinetics.

}, doi = {10.3390/molecules15107035}, author = {Kelkel, Mareike and Jacob, Claus and Dicato, Mario and Diederich, Marc F.} } @article {1024, title = {Untersuchungen zum zellul{\"a}ren Mechanismus der ER/Cytosol-Retrotranslokation einer cytotoxischen alpha-Variante des viralen A/B-Toxins K28 der Hefe}, year = {2009}, author = {Kelkel, Mareike} }